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Problemy bioetyczne ingerencji medycznych zaburzających genetyczne i epigenetyczne uwarunkowania rozwoju człowieka
Midro, Alina T.; Hoser, Henryk F. (Redakcja Wydawnictw Wydziału Teologicznego Uniwersytetu Opolskiego, 2015)
Introduction to the practice of modern medical procedures disturbing genetic and epigenetic determinants of human development leading to genetic disorders and/or reduced survival as a result of congenital malformations raises a number of bioethical problems. Due to its genetic and biological basis of its functioning the human being is a human being from the conception. From the point of view of a clinical geneticist, procreation of a new human being is the creation of a new individual genome, that is database on the genetic information obtained from the parents through their reproductive cells and then starting the duplication and imprinting (labelling), and creating opportunities for its reading and modifying in the course of further development (gene expression and its regulation). In the article there are discussed problems arising from health risk, life and dignity of the child and their parents resulting from the use of in vitro fertilization methods.
Tożsamość płci od poczęcia – spojrzenie genetyka
Midro, Alina T. (Redakcja Wydawnictw Wydziału Teologicznego Uniwersytetu Opolskiego, 2016)
Femininity and masculinity associated with human identity is genetically determined from the beginning of the individual human being. The diverse genetic material with the appropriate software epigenetic characteristic of a particular gender is introduced at the moment of conception due to sperm penetrating to the egg. It is then that the process of molecular changes that differentiate sex of cells and thus the whole organism of the human person is initiated. Different genes and regulators are involved in shaping the characteristics of the female or male human body and forms of their behavior. They reveal their activity depending on the developmental age of the body and the functions of individual tissues and organs forming a related system known as sexome. Regulatory mechanisms of the genome software called the epigenome responding well to environmental influences belong to the elements performing in a network of links. Therefore, the genetically and epigenetically determined sexual dimorphism of human beings is a natural way of their social and cultural development.